D

I

DE SANTO , Irene

Last name: DE SANTO

First name: Irene

2018 (v1)

Publication

Metadata-only

CDK 4/6 Inhibitors as Single Agent in Advanced Solid Tumors

Schettini, Francesco De Santo, Irene Rea, Carmen G

Cyclin-dependent kinases (CDK) 4/6 inhibitors, namely abemaciclib, palbociclib, and ribociclib, interfere with cell cycle progression, induce cell senescence and might promote cancer cell disruption by a cytotoxic T cells-mediated effect. Phase III randomized clinical trials have proven that CDK4/6 inhibitors (CDK4/6i) in combination with...

Uploaded on: April 14, 2023