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DELNESTE , Yves

Last name: DELNESTE

First name: Yves

June 19, 2014 (v1)

Journal article

Metadata-only

Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways.

Marion, Estelle Song, Ok-Ryul Christophe, Thierry

Mycobacterium ulcerans, the etiological agent of Buruli ulcer, causes extensive skin lesions, which despite their severity are not accompanied by pain. It was previously thought that this remarkable analgesia is ensured by direct nerve cell destruction. We demonstrate here that M. ulcerans-induced hypoesthesia is instead achieved through a...

Uploaded on: March 26, 2023
November 11, 2019 (v1)

Journal article

Metadata-only

Sequential mutational evaluation of CALR ‐mutated myeloproliferative neoplasms with thrombocytosis reveals an association between CALR allele burden evolution and disease progression

Cottin, Laurane Riou, Jeremie Orvain, Corentin

In myeloproliferative neoplasms (MPN), JAK2V617F allele burden measurement has an impact on prognosis that helps in patient monitoring. Less is known about its usefulness in CALR-mutated cases. Additional mutations found by next-generation sequencing have also shown an impact on prognosis that may drive therapeutic choices, especially in...

Uploaded on: December 4, 2022