Non communiqué
-
December 7, 2018 (v1)PublicationUploaded on: December 4, 2022
-
July 13, 2018 (v1)Journal article
Bone morphogenetic protein 9 (BMP9) and BMP10 are thetwo high-affinity ligands for the endothelial receptor activinreceptor-like kinase 1 (ALK1) and are key regulators of vascularremodeling. They are both present in the blood, buttheir respective biological activities are still a matter ofdebate. The aim of the present work was to characterize...
Uploaded on: December 4, 2022 -
March 28, 2018 (v1)Journal article
In BRAFV600E melanoma cells, a global metabolomic analysis discloses a decrease in nicotinamide adenine dinucleotide (NAD+) levels upon PLX4032 treatment that is conveyed by a STAT5 inhibition and a transcriptional regulation of the nicotinamide phosphoribosyltransferase (NAMPT) gene. NAMPT inhibition decreases melanoma cell proliferation both...
Uploaded on: December 4, 2022 -
July 2018 (v1)Journal article
Advanced cutaneous melanoma is one of the most challenging cancers to treat because of its high plasticity, metastatic potential, and resistance to treatment. New targeted therapies and immunotherapies have shown remarkable clinical efficacy. However, such treatments are limited to a subset of patients and relapses often occur, warranting...
Uploaded on: December 4, 2022 -
April 20, 2018 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
April 20, 2018 (v1)Journal article
International audience
Uploaded on: February 22, 2023 -
August 22, 2017 (v1)Journal article
Extracellular vesicles (EVs) have been shown to play an important role in intercellular communication as carriers of DNA, RNA and proteins. While the intercellular transfer of miRNA through EVs has been extensively studied, the stability of extracellular miRNA (ex-miRNA) once engulfed by a recipient cell remains to be determined. Here, we...
Uploaded on: December 4, 2022