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2005 (v1)Journal article
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August 2007 (v1)Journal article
We studied the mechanism of action and the binding site of APETx1, a peptide toxin purified from sea anemone, on the human ether-a-go-go-related gene (hERG) channel. Similar to the effects of gating modifier toxins (hanatoxin and SGTx) on the voltage-gated potassium (Kv) 2.1 channel, APETx1 shifts the voltage-dependence of hERG activation in...
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2003 (v1)Journal article
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2005 (v1)Journal article
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February 2007 (v1)Journal article
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2005 (v1)Journal article
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2003 (v1)Journal article
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2002 (v1)Journal article
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2002 (v1)Journal article
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2006 (v1)Journal article
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2006 (v1)Journal article
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2004 (v1)Journal articleA new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons
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2004 (v1)Journal articleA new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons
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2005 (v1)Journal article
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2005 (v1)Journal article
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2004 (v1)Journal article
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2004 (v1)Journal article
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October 29, 2020 (v1)Publication
Introduction: Selective blockers are important tools for identifying the physiological role of ion channels isoforms. L-type calcium channels are high voltage activated channels sensitive to dihydropyridine (DHP). Two distinct isoforms (1C/Cav1.2 and 1D/Cav1.3) mediate calcium entry into cardiac cells to trigger contraction or contribute to...
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2006 (v1)Journal article
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2006 (v1)Journal article
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