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DOELKER , Eric

Last name: DOELKER

First name: Eric

January 3, 2024 (v1)

Publication

Metadata-only

Towards elucidation of the drug release mechanism from compressed hydrophilic matrices made of cellulose ethers. III. Critical use of thermodynamic parameters of activation for modeling the water penetration and drug release processes

Ferrero Rodríguez, Carmen Massuelle, Danielle Jeannerat, Damien

The two main purposes of this work were: (i) to critically consider the use of thermodynamic parameters of activation for elucidating the drug release mechanism from hydroxypropyl methylcellulose (HPMC) matrices, and (ii) to examine the effect of neutral (pH 6) and acidic (pH 2) media on the release mechanism. For this, caffeine was chosen as...

Uploaded on: January 5, 2024