DOMBRET , Herve

Last name: DOMBRET

First name: Herve

2018 (v1)

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Oncogenic Predictors of Outcome in Older AML Patients Treated Intensively. Analysis of the ALFA-1200 Trial

Itzykson, Raphael Fournier, Elise Braun, Thorsten

60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA, DEC 01-04, 2018

Uploaded on: December 3, 2022
2021 (v1)

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Genetic identification of patients with AML older than 60 years achieving long-term survival with intensive chemotherapy

Itzykson, Raphael Fournier, Elise Berthon, Celine

To design a simple and reproducible classifier predicting the overall survival (OS) of patients with acute myeloid leukemia (AML) >= 60 years of age treated with 7+3, we sequenced 37 genes in 471patients fromtheALFA1200 (Acute Leukemia FrenchAssociation) study (median age, 68 years). Mutation patterns and OS differed between the 84 patients...

Uploaded on: December 3, 2022
November 15, 2022 (v1)

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Blinatumomab during Consolidation in High-Risk Philadelphia Chromosome (Ph)-Negative B-Cell Precursor (BCP) Acute Lymphoblastic Leukemia (ALL) Adult Patients: A Two-Cohort Comparison within the Graall-2014/B Study

Boissel, Nicolas Huguet, Francoise Leguay, Thibaut

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Uploaded on: October 11, 2023
November 15, 2022 (v1)

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In Adults with Ph-Negative Acute Lymphoblastic Leukemia (ALL), Age-Adapted Chemotherapy Intensity and MRD-Driven Transplant Indication Significantly Reduces Treatment-Related Mortality (TRM) and Improves Overall Survival - Results from the Graall-2014 Trial

Boissel, Nicolas Huguet, Francoise Leguay, Thibaut

Background During the 2005-2014 period, the GRAALL conducted the GRAALL-2005 trial in patients (pts) with Philadelphia chromosome (Ph)-negative ALL aged 18-59y. In this trial, all pts received a pediatric-inspired chemotherapy, whatever their age. Post-hoc analysis revealed an unacceptable TRM in pts aged 45-59y (Huguet et al. J Clin Oncol...

Uploaded on: March 25, 2023

DOMBRET , Herve

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