D

V

DRIFFORT , V.

Last name: DRIFFORT

First name: V.

October 30, 2013 (v1)

Journal article

Metadata-only

NaV1.5 Na+ channels allosterically regulate the NHE-1 exchanger and promote the activity of breast cancer cell invadopodia

Brisson, L. Driffort, V. Benoist, L.

The degradation of the extracellular matrix by cancer cells represents an essential step in metastatic progression and this is performed by cancer cell structures called invadopodia. Na V 1.5 (also known as SCN5A) Na + channels are overexpressed in breast cancer tumours and are associated with metastatic occurrence. It has been previously shown...

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