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DUBUQUOY , Laurent

Last name: DUBUQUOY

First name: Laurent

April 2, 2001 (v1)

Journal article

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Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer

Desreumaux, Pierre Dubuquoy, Laurent Nutten, Sophie

The peroxisome proliferator–activated receptor γ (PPARγ) is highly expressed in the colon mucosa and its activation has been reported to protect against colitis. We studied the involvement of PPARγ and its heterodimeric partner, the retinoid X receptor (RXR) in intestinal inflammatory responses. PPARγ1/− and RXRα1/− mice both displayed a...

Uploaded on: May 28, 2023
2013 (v1)

Journal article

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Functional Polymorphisms in the Regulatory Regions of the VNN1 Gene Are Associated with Susceptibility to Inflammatory Bowel Diseases

Gensollen, Thomas Bourges, Christophe Rihet, Pascal

no abstract

Uploaded on: February 28, 2023
March 2008 (v1)

Journal article

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NOD2: a potential target for regulating liver injury.

Body-Malapel, Mathilde Dharancy, Sébastien Berrebi, Dominique

The recent discovery of bacterial receptors such as NOD2 that contribute to crosstalk between innate and adaptive immune systems in the digestive tract constitutes an important challenge in our understanding of liver injury mechanisms. The present study focuses on NOD2 functions during liver injury. NOD2, TNF-alpha and IFN-gamma mRNA were...

Uploaded on: December 4, 2022