DUCHATEAU , Nicolas

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Myocardial shape and deformation are two relevant descriptors for the study of cardiac function and can undergo strong interactions depending on diseases. Manifold learning provides low dimensional representations of these high-dimensional descriptors, but the choice of normalization can strongly affect the analysis. Besides, whether the shape...

Collecting large databases of annotated medical images is crucial for the validation and testing of feature extraction, statistical analysis and machine learning algorithms. Recent advances in cardiac electromechanical modeling and image synthesis provided a framework to generate synthetic images based on realistic mesh simulations....

We present a novel automated method to segment the my-ocardium of both left and right ventricles in MRI volumes. The segmen-tation is consistent in 3D across the slices such that it can be directly used for mesh generation. Two specific neural networks with multi-scale coarse-to-fine prediction structure are proposed to cope with the small...

We propose a method based on deep learning to perform cardiac segmentation on short axis MRI image stacks iteratively from the top slice (around the base) to the bottom slice (around the apex). At each iteration, a novel variant of U-net is applied to propagate the segmentation of a slice to the adjacent slice below it. In other words, the...

Cardiac shape and deformation are two relevant descriptors for the characterization of cardiovascular diseases. It is also known that strong interactions exist between them depending on the disease. In clinical routine, these high dimensional descriptors are reduced to scalar values (ventricular ejection fraction, volumes, global strains...),...

This case illustrates the evolution of right ventricular (RV) 3-dimensional (3D) area strain during pregnancy in a patient with repaired Tetralogy of Fallot. The report highlights impairment in RV function with pregnancy, suggesting the importance of prepregnancy RV systolic function assessment, especially using 3D echocardiography.

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Background: Right ventricular (RV) function assessment is crucial in CHD patients, especially in atrial septaldefect (ASD) and Tetralogy of Fallot (TOF) patients. Indeed, prognosis is very different between TOF patientswith pulmonary regurgitation and ASD patients, and only little is known about 3D deformation in RV overload. Purpose: The aim...

Cardiac motion contains information underlying disease development , and complements the anatomical information extracted for each subject. However, normalization of temporal trajectories is necessary due to anatomical differences between subjects. In this study, we encode inter-subject shape variations and temporal deformations in a common...

This chapter focuses on how we can best predict the future health of patients, known as prognosis. This encompasses areas such as risk prediction and predicting response to treatment. A clinical opinion piece summarises the role of prognosis in clinical care and highlights the areas where AI has already had an impact in this area. The technical...

International audience

International audience

BackgroundOutcomes in pulmonary hypertension (PH) are related to right ventricular (RV) function andremodeling. We hypothesized that changes in RV function, especially area strain (AS), couldprovide incremental prognostic data.PurposeTo assess global and regional 3D RV function changes between baseline and 6-months visit andevaluate their...

International audience

BackgroundOutcomes in pulmonary hypertension (PH) are related to right ventricular (RV) function andremodeling. We hypothesized that changes in RV function, especially area strain (AS), couldprovide incremental prognostic data.PurposeTo assess global and regional 3D RV function changes between baseline and 6-months visit andevaluate their...

Background: Pulmonary embolism (PE) is a common life-threatening disease, with mortality related to right ventricular (RV) dysfunction. Aims: To investigate the value of 3D global and regional right ventricular strain in patients with acute PE and at 1 month, as compared to a control population.Methods and Results: We conducted a longitudinal...

Background : Outcomes in pulmonary hypertension (PH) are related to right ventricular (RV) function and remodeling. We hypothesized that changes in RV function and especially area strain (AS) could provide incremental prognostic information compared to the use of baseline data only. We therefore aimed to assess RV function changes between...

International audience

International audience

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