E. BOTTINO

The recent progress in both neurobiology and microelectronics suggests the creation of new, powerful tools to investigate the basic mechanisms of brain functionality. In particular, a lot of efforts are spent by scientific community to define new frameworks devoted to the analysis of in-vitro cultured neurons. One possible approach is recording...

This paper reports the design and the experimental results of a fully integrated, low-noise, low-power standard CMOS preamplifier circuit used to record the extracellular electrophysiological activity of in vitro biological neuronal cultures. Our goal is to use the preamplifier in a fully integrated, multi-channel, bi-directional...