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EBENEZER , Philip J.

Last name: EBENEZER

First name: Philip J.

December 12, 2017 (v1)

Publication

Metadata-only

Amino acid analog toxicity in primary rat neuronal and astrocyte cultures: implications for protein misfolding and tdp-43 regulation

Dasuri, Kalavathi Ebenezer, Philip J. Uranga, Romina M.

Amino acid analogs promote translational errors that result in aberrant protein synthesis, and have been used to understand the effects of protein misfolding in a variety of physiological and pathological settings. TDP-43 is a protein that is linked to protein aggregation and toxicity in a variety of neurodegenerative diseases. In this study we...

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