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C

ELL , C

Last name: ELL

First name: C

2012 (v1)

Publication

Metadata-only

Gastric exocrine and endocrine cell morphology under prolonged acid inhibition therapy: results of a 5-year follow-up in the LOTUS trial.

FIOCCA, ROBERTO MASTRACCI, LUCA Attwood, SE

Background Sustained acid inhibition with PPI stimulates gastrin secretion, exerting a proliferative drive on enterochromaffin-like cells (ECL cells) of the oxyntic mucosa. It may also accelerate development of gastric gland atrophy in Helicobacter pylori-infected individuals. Aims To evaluate gastric exocrine and endocrine cell changes in GERD...

Uploaded on: April 14, 2023
2015 (v1)

Publication

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Long-term safety of proton pump inhibitor therapy assessed under controlled, randomised clinical trial conditions: data from the SOPRAN and LOTUS studies

Attwood, SE Ell, C Galmiche, JP

Control of chronic gastro-oesophageal reflux disease may be achieved either by anti-reflux surgery (ARS) or by long-term medical therapy with proton pump inhibitors (PPIs). The primary efficacy results of the SOPRAN study, comparing long-term omeprazole use with open ARS, and the LOTUS study, comparing long-term esomeprazole use with...

Uploaded on: March 27, 2023