BackgroundCryptorchidism, the most frequent congenital malformation in full-term male newborns, increases the risk of hypofertility and testicular cancer. Most cases remain idiopathic but epidemiological and experimental studies have suggested a role of both genetic and environmental factors. Physiological testicular descent is regulated by two...
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2015 (v1)Journal articleUploaded on: December 4, 2022
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2019 (v1)Journal article
Cryptorchidism, a frequent genital malformation in male newborn, remains in most cases idiopathic. On the basis of experimental, epidemiological, and clinical data, it has been included in the testicular dysgenesis syndrome and believed to be influenced, together with genetic and anatomic factors, by maternal exposure to endocrine disrupting...
Uploaded on: December 4, 2022 -
December 16, 2016 (v1)Journal article
Introduction: Bariatric surgery including the Roux-en-Y Gastric Bypass (RYGB) and the laparoscopic sleeve gastrectomy (LSG) is a well-established therapeutic option for patients with morbid or severe obesity. Metabolic modifications observed after bariatric surgery are thought to be, at least partly, linked to hormonal changes. While variation...
Uploaded on: February 28, 2023 -
December 1, 2009 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
May 20, 2017 (v1)Publication
Persistent organic pollutants (POPs) are environmental contaminants that interfere with normal hormonal homeostasis and act as endocrine disrupting compounds (EDC). These molecules can mimic hormone effects on metabolism. The links between metabolism and cancer are now well established. Metabolism generates reactive oxygen species (ROS), which...
Uploaded on: February 28, 2023 -
May 9, 2017 (v1)Publication
Persistent organic pollutants (POPs) are environmental contaminants that interfere with normal hormonal homeostasis and act as endocrine disrupting compounds (EDC). These molecules can mimic hormone effects on metabolism. The links between metabolism and cancer are now well established. Metabolism generates reactive oxygen species (ROS), which...
Uploaded on: February 28, 2023 -
2020 (v1)Journal article
Background: Pollution – unwanted waste released to air, water, and land by human activity – is the largest environmental cause of disease in the world today. It is responsible for an estimated nine million premature deaths per year, enormous economic losses, erosion of human capital, and degradation of ecosystems. Ocean pollution is an...
Uploaded on: December 4, 2022