2009 (v1)
Publication
The X-ray crystallog. coordinates of the Abl tyrosine kinase domain in its active, inactive, and Src-like inactive conformations were used as targets to simulate the binding mode of a large series of pyrazolo[3,4-d]pyrimidines (known Abl inhibitors) by means of GOLD software. Receptor-based alignments provided by mol. docking calcns. were...
Uploaded on: May 13, 2023