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FERRINI , Silvano

Last name: FERRINI

First name: Silvano

2011 (v1)

Publication

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HGF-producing mesenchymal stromal cells support chronic lymphocytic leukemic B cells survival

GIANNONI, PAOLO QUARTO, RODOLFO FLORIO, TULLIO

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Uploaded on: April 14, 2023
2014 (v1)

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Recombinant IL-21 and anti-CD4 antibodies cooperate in syngeneic neuroblastoma immunotherapy and mediate long-lasting immunity

RIGO, VALENTINA ORENGO, ANNA MARIA BRIZZOLARA, ANTONELLA

IL-21 is an immune-enhancing cytokine, which showed promising results in cancer immunotherapy. We previously observed that the administration of anti-CD4 cell-depleting antibody strongly enhanced the anti-tumor effects of an IL-21-engineered neuroblastoma (NB) cell vaccine. Here, we studied the therapeutic effects of a combination of...

Uploaded on: April 14, 2023
2016 (v1)

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Proteomic analysis uncovers common effects of IFN-γ and IL-27 on the HLA class I antigen presentation machinery in human cancer cells

Petretto, Andrea Carbotti, Grazia Inglese, Elvira

IL-27, a member of the IL-12-family of cytokines, has shown anti-tumor activity in several pre-clinical models due to anti-proliferative, anti-angiogenic and immune-enhancing effects. On the other hand, IL-27 demonstrated immune regulatory activities and inhibition of auto-immunity in mouse models. Also, we reported that IL-27, similar to...

Uploaded on: April 14, 2023