FILACI , Gilberto

The CD8+ T suppressor lymphocytes identified in humans belong to three different subpopulations. All of them inhibit the proliferation of antigen-specific T cells. The type 1 and type 2 of CD8+ T suppressor cells are characterized by the CD8+CD28− phenotype, while no detailed data are available at the moment on the phenotype of the type 3 of...

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Vaccino peptidico antitumorale

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Cancer vaccines represent a promising therapeutic approach for which prime time is imminent. However, clinical efficacy must be improved in order for cancer vaccines to become a valid alternative or complement to traditional cancer treatments. Considerable efforts have been undertaken so far to better understand the fundamental requirements for...

Often researchers find it difficult to interpret and correlate the results obtained from several experiments thus the development of a system that would allow storage, display and data analysis would be very useful. A web based interface is presented that allows people from a laboratory to submit the collected data and to compare results within...

A nanoarray or microarray of antibodies comprising a planar surface having an ultraflat surface is described, which is characterized in that it comprises a planar substrate functionalized with a first monolayer of linking molecules, preferably APTES molecules, and a second monolayer of small peptides of the general formula (I) capable of...

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Background: The autoimmune regulator (AIRE) gene has been shown to be involved in the genesis of autoimmunity in subjects affected by the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), and more recently in the pathogenesis of alopecia. Considering that SSc, object of the present study, has a deep cutaneous involvement,...