FRACCARO , Paolo

Clinical Trials (CTs) play an increasingly important role in modern medicine. Often these types of studies, especially in the final phases, require collaboration between several hospitals, laboratories and institutions in different places or countries. The solution proposed is a template which exploits the principles of Networked Clinical...

The aim of the MEDINFO HIV Clinical Network project is to focus on the development of a web-based system that allows cooperative work between the departments of Infectious Diseases (DoIDs) and the Immunology Laboratories (IL), which are located in Liguria and Piedmont; in order to carry out multicentric Clinical Studies. The working group is...

The solution described in this paper is a web tool to access and manage patients' data in Ophthalmology. Clinical data are collected in a database through a system that can be easily utilized by physicians and internal information can be extracted for statistical purposes. The platform is also available for simultaneous Multicenter Clinical...

Background: Clinical Trials (CTs) are indispensable instruments for evidence-based medicine and frequently necessitate the management, sharing and analysis of large amounts of data amongst partners in different locations. Methods: To effectively satisfy these requirements, the proposed solution combines a web platform and a Clinical Data...

Nowadays, most healthcare providers archive and manage patients' information in electronic format. The reuse of such Clinical Information is essential from both a scientific and financial perspective, and for the integration of Primary Care and Clinical Research; which has become a principal goal. The solution proposed aims at integrating data...

Abstract: Nel contesto sanitario, l'utilizzo dell'Information and Communication Technology (ICT) è diventato uno strumento fondamentale. A tale proposito, anche la Commissione Europea si è espressa in tale senso ("eHealth Action Plan 2012-2020 - Innovative healthcare for the 21st century", Brussels, 6.12.2012) evidenziando l'importanza...

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Introduzione. Nonostante gli indiscutibili successi ottenuti con la HAART, alcuni pazienti con infezione da HIV necessitano di ricovero ospedaliero per l'insorgere di comorbidita'. Obiettivo del nostro lavoro è definire le cause che rendono necessaria l'ospedalizzazione nei pazienti con infezione da HIV nella nostra regione. Pazienti e...

Background. This study reviews recent trends of HIV inpatient admissions in two HIV centres in Europe. Method Chelsea and Westminster Hospital, London (UK) and four infectious diseases departments in Liguria, Italy (IT) collected data on inpatient HIV admissions from January to December 2012, including patient demographic, discharge diagnoses,...

Background: In recent years, Highly-Active Anti-Retroviral Therapies (HAARTs) have modified the Human Immunodeficiency Virus (HIV) life-cycle and the disease is now considered chronic. Consequently, a longitudinal and complex follow-up is now required for HIV positive patients during their lifetime. Moreover, patients often encounter various...

Nowadays, many healthcare providers archive and manage patients' data in an electronic format. The reuse of such clinical information is essential from both a scientific and financial perspective; and for the integration of primary care and clinical research, which has become a main goal. The objective of the proposed solution is the...

Scopo dello studio: valutare la durability, la safety e il recupero immunologico in una coorte di pazienti (pz) HIV positivi (+) in terapia con Maraviroc (MVC) Metodi: Sono stati analizzati i dati di pz HIV + in terapia antiretrovirale (ART) contenente MVC almeno da 6 mesi (tutti con virus CCR-5 tropico secondo l'analisi genotipica e...

INTRODUCTION: The persistence of immune activation and inflammation in HIV patients with HIV-RNA (VL) undetectable causes many co-morbidities [1-3]. The aim of this study is to correlate monocytes (m) and NK cell activation levels, soluble markers and oxidative stress with clinical, biochemical and metabolic data in HIV-1 infected patients...

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Purpose of the study: Promising research suggest that maraviroc (MVC) has favourable clinical outcome in HIV-infected patients (pts). Aim of the study is to assess: durability, safety profile and immunovirological recovery in a large MVC-based cohort. Methods: All HIV pts treated with antiretroviral therapy (ART) containing MVC for at least 6...