In western countries, exudative age-related macular degeneration (AMD) is one of the leading causes of blindness in the elderly. This disease is characterized by an abnormal vascularization of the choroid and a strong intraocular inflammation. Currently, only anti-VEGF symptomatic treatments exist, which rely on humanized monoclonal antibodies...
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June 25, 2021 (v1)PublicationUploaded on: October 11, 2023
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July 18, 2022 (v1)Publication
Ce dossier de Laboratoire italien fait suite à un numéro consacré aux Voix et parcours du féminisme dans les revues de femmes (1870-1970) et propose un premier état des lieux des revues féministes italiennes depuis les années 1970 jusqu'au tournant numérique du nouveau millénaire et à la dimension transnationale des féminismes contemporains.
Uploaded on: December 3, 2022 -
2019 (v1)Journal article
We report herein the synthesis of a newly described anti-cancer agent, NRPa-308. This compound antagonizes Neuropilin-1, a multi-partners transmembrane receptor overexpressed in numerous tumors, and thereby validated as promising target in oncology. The preparation of NRPa-308 proved challenging because of the ortho-gonality of the amide and...
Uploaded on: December 4, 2022