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FARISELLO , Pasqualina

Last name: FARISELLO

First name: Pasqualina

2017 (v1)

Publication

Metadata-only

Impaired GABAB-mediated presynaptic inhibition increases excitatory strength and alters short-term plasticity in synapsin knockout mice

Valente, Pierluigi Farisello, Pasqualina Valtorta, Flavia

Synapsins are a family of synaptic vesicle phosphoproteins regulating synaptic transmission and plasticity. SYN1/2 genes are major epilepsy susceptibility genes in humans. Consistently, synapsin I/II/III triple knockout (TKO) mice are epileptic and exhibit severe impairments in phasic and tonic GABAergic inhibition that precede the appearance...

Uploaded on: April 14, 2023