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FERECATU , Ioana

Last name: FERECATU

First name: Ioana

March 29, 2018 (v1)

Journal article

Metadata-only

Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation

Ferecatu, Ioana Canal, Frederic Fabbri, Lucilla

Biogenesis of iron-sulfur clusters (ISC) is essential to almost all forms of life and involves complex protein machineries. This process is initiated within the mitochondrial matrix by the ISC assembly machinery. Cohort and case report studies have linked mutations in ISC assembly machinery to severe mitochondrial diseases. The...

Uploaded on: December 4, 2022