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FERRAT , Gilles

Last name: FERRAT

First name: Gilles

2004 (v1)

Journal article

Metadata-only

Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus

Chagot, Benjamin Escoubas, Pierre Villegas, Elba

Animal toxins block voltage-dependent potassium channels (Kv) either by occluding the conduction pore (pore blockers) or by modifying the channel gating properties (gating modifiers). Gating modifiers of Kv channels bind to four equivalent extracellular sites near the S3 and S4 segments, close to the voltage sensor. Phrixotoxins are gating...

Uploaded on: February 28, 2023