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FIORINI , Laura

Last name: FIORINI

First name: Laura

2015 (v1)

Journal article

Metadata-only

The Hedgehog receptor Patched: A new target for cancer treatment, first inhibitors of the multidrug resistance activity of Patched

Fiorini, Laura Tribalat, Marie-Aude Sauvard, Lucy

no abstract

Uploaded on: February 28, 2023
September 2015 (v1)

Journal article

Metadata-only

Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of Patched and increase chemotherapy efficiency on melanoma cells

Fiorini, Laura Tribalat, Marie-Aude Sauvard, Lucy

Multidrug resistance has appeared to mitigate the efficiency of anticancer drugs and the possibility of successful cancer chemotherapy. The Hedgehog receptor Patched is a multidrug transporter expressed in several cancers and as such it represents a new target to circumvent chemotherapy resistance. We report herein that paniceins and especially...

Uploaded on: February 28, 2023