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FIORINO , G

Last name: FIORINO

First name: G

2010 (v1)

Publication

Metadata-only

An Alu-like RNA promotes cell differentiation and reduces malignancy of human neuroblastoma cells.

CASTELNUOVO, MANUELE MASSONE, SARA TASSO, ROBERTA

Neuroblastoma (NB) is a pediatric cancer characterized by remarkable cell heterogeneity within the tumor nodules. Here, we demonstrate that the synthesis of a pol III-transcribed non-coding (nc) RNA (NDM29) strongly restricts NB development by promoting cell differentiation, a drop of malignancy processes and a dramatic reduction of the tumor...

Uploaded on: April 14, 2023