F

J

FISCHEL , J. L.

Last name: FISCHEL

First name: J. L.

August 2007 (v1)

Journal article

Metadata-only

Role of the HER2 [Ile655Val] genetic polymorphism in tumorogenesis and in the risk of trastuzumab-related cardiotoxicity.

Beauclair, S. Formento, P. Fischel, J. L.

BACKGROUND: To examine the impact of a frequent her2 gene polymorphism (Ile655Val) on tumor growth and on the pharmacodynamics of treatment by trastuzumab. PATIENTS AND METHODS: Experimental study: The growth characteristics of cells expressing the Ile or Val isoform were examined in vitro and after injection into nude mice. The effect of...

Uploaded on: December 4, 2022