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FLORES DE MERA , María De La Luz

Last name: FLORES DE MERA

First name: María De La Luz

August 24, 2016 (v1)

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Bases moleculares de la resistencia a taxanos y nuevas alternativas terapéuticas en el cáncer avanzado de mama y próstata

Flores de Mera, María de la Luz

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Uploaded on: December 4, 2022
June 20, 2017 (v1)

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Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer

Gasca, Jessica Flores de Mera, María de la Luz Giraldez Macias, Servando

FBXW7 is a component of SCF (complex of SKP1, CUL1 and F-box-protein)-type ubiquitin ligases that targets several oncoproteins for ubiquitination and degradation by the proteasome. FBXW7 regulates cellular apoptosis by targeting MCL1 for ubiquitination. Recently, we identified PLK1 as a new substrate of FBXW7 modulating the intra-S-phase...

Uploaded on: March 25, 2023