FORCIOLI-CONTI , Nicolas

The primary cilium (PC) is an organelle present in almost all cell types of the organism. During development, the PC plays an important function by driving signaling pathways such as Hedgehog or Wnt. Some genetic syndromes affecting specifically the PC are associated with obesity. My project has consisted to analyze the evolution of the PC...

The primary cilium is an organelle present in most of the cells of the organism. Ciliopathies are genetic disorders of the primary cilium and can be associated with obesity. We have studied the primary cilium during adipocyte differentiation of human adipose stem cells (hASC). We show here that the size of the primary cilium follows several...

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