The aim of this paper is to show the necessity of a semantic approach to the concept of'aspect' in the Scienza nuova, as well as to defend a particular way of philosophical comprehension. From a philosophical point of view, the dimension of aspectuality is in the origin of the correlation between imaginative perception on the one hand, and...
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October 7, 2016 (v1)PublicationUploaded on: March 27, 2023
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November 17, 2022 (v1)Journal article
Abstract High levels of human group IIA secreted phospholipase A 2 (hGIIA) have been associated with various inflammatory disease conditions. We have recently shown that hGIIA activity and concentration are increased in the plasma of patients with hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE) and negatively correlate with...
Uploaded on: December 3, 2022 -
2022 (v1)PublicationGenotype-phenotype correlations and disease mechanisms in PEX13-related Zellweger spectrum disorders
Background Pathogenic variants in PEX-genes can affect peroxisome assembly and function and cause Zellweger spectrum disorders (ZSDs), characterized by variable phenotypes in terms of disease severity, age of onset and clinical presentations. So far, defects in at least 15 PEX-genes have been implicated in Mendelian diseases, but in some of the...
Uploaded on: February 14, 2024 -
2019 (v1)Publication
Axon pathfinding and synapse formation are essential processes for nervous system development and function. The assembly of myelinated fibres and nodes of Ranvier is mediated by a number of cell adhesion molecules of the immunoglobulin superfamily including neurofascin, encoded by the NFASC gene, and its alternative isoforms Nfasc186 and...
Uploaded on: April 14, 2023