FOUSSAT , Arnaud

Introduction: Regulatory T (Treg) cells play a crucial role in preventing autoimmune diseases and are an idealtarget for the development of therapies designed to suppress inflammation in an antigen-specific manner.Type 1 regulatory T (Tr1) cells are defined by their capacity to produce high levels of interleukin 10 (IL-10), whichcontributes to...

BACKGROUND & AIMS: New therapeutic strategies are needed for patients with refractory Crohn's Disease (CD). We evaluated data from the Crohn's and T-regulatory Cell Study (CATS)1 to determine safety and efficacy of antigen-specific T regulatory (Treg) cells for treatment of refractory CD. METHODS: We performed a 12-week, open-labelled,...