FRANCESCA BACCHETTI

Last name: FRANCESCA BACCHETTI

2024 (v1)

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Therapeutic effect of extracellular vesicles derived from mesenchymal stem cells in amyotrophic lateral sclerosis

Francesca Bacchetti Matilde Balbi Giunti Debora

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Uploaded on: July 3, 2024
2022 (v1)

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The negative allosteric modulator CTEP ameliorates the reactive phenotype of human-derived iAstrocytes differentiated from iNPCs of patients affected by Amyotrophic Lateral Sclerosis

Tessitore Sara Torazza Carola Kumar Mandeep

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Uploaded on: July 3, 2024
2023 (v1)

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microRNAs shuttled by extracellular vesicles derived from mesenchymal stem cells revert glial activation and neurotoxicity in in-vitro models of amyotrophic lateral sclerosis

Milanese Marco Matilde Balbi Giunti Debora

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the selective death of motoneurons (MNs). ALS is also defined a non-cell-autonomous disease, due to the contribution of glial cells that acquire an aberrant reactive phenotype and secrete neurotoxic factors toward MN. At present there is no effective cure for...

Uploaded on: July 3, 2024
2024 (v1)

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In-vitro and in-vivo studies showing the beneficial effects of extracellular vesicles derived from mesenchymal stem cells on the reactive astrocyte activation in amyotrophic lateral sclerosis

Francesca Bacchetti Matilde Balbi Giunti Debora

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Uploaded on: August 14, 2024
2023 (v1)

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In-vitro and in-vivo evidence supporting the therapeutic effect of extracellular vesicles derived from mesenchymal stem cells in amyotrophic lateral sclerosis

Milanese Marco Matilde Balbi Giunti Debora

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the selective death of motoneurons (MNs). Despite significant progress the precise pathological mechanisms of MN death remain largely obscure. ALS is also defined a non-cell-autonomous disease, due to the contribution of glial cells that acquire an...

Uploaded on: July 3, 2024
2023 (v1)

Publication

Metadata-only

In-vitro and in-vivo evidence supporting the therapeutic effect of extracellular vesicles derived from mesenchymal stem cells in amyotrophic lateral sclerosis

Milanese Marco Matilde Balbi Giunti Debora

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the selective death of motoneurons (MNs). Despite significant progress the precise pathological mechanisms of MN death remain largely obscure. ALS is also defined a non-cell-autonomous disease, due to the contribution of glial cells that acquire an...

Uploaded on: July 3, 2024
2024 (v1)

Publication

Metadata-only

Reactive Astrocytes from patients affected by Amyotrophic Lateral Sclerosis: how mGlu5 receptor modulation affects pathological features

Sara Tessitore Carola Torazza Francesca Bacchetti

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Uploaded on: October 15, 2024
2024 (v1)

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mGlu5 receptor negative allosteric modulation reduces the aberrant cellular reactivity and neurotoxicity of reactive human astrocytes differentiated from fibroblast of SOD1 and C9orf72 ALS patients

Sara Tessitore Carola Torazza Mandeep Kumar

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Uploaded on: October 15, 2024

FRANCESCA BACCHETTI

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