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FRANKEL , Gad

Last name: FRANKEL

First name: Gad

2024 (v1)

Publication

Metadata-only

Functional features of KPC-109, a novel 270-loop KPC-3 mutant mediating resistance to avibactam-based β-lactamase inhibitor combinations and cefiderocol

Di Pilato, Vincenzo Codda, Giulia Niccolai, Claudia

Objectives: To investigate a ceftazidime/avibactam (CZA)-resistant Klebsiella pneumoniae (NE368), isolated from a patient exposed to CZA, expressing a novel K. pneumoniae carbapenemase (KPC)-3 variant (KPC109). Methods: Antimicrobial susceptibility testing was performed by reference broth microdilution. Wholegenome sequencing (WGS) analysis of...

Uploaded on: March 3, 2024
2024 (v1)

Publication

Metadata-only

Functional features of KPC-109, a novel 270-loop KPC-3 mutant mediating resistance to avibactam-based β-lactamase inhibitor combinations and cefiderocol

Di Pilato, Vincenzo Codda, Giulia Niccolai, Claudia

Objectives: To investigate a ceftazidime/avibactam (CZA)-resistant Klebsiella pneumoniae (NE368), isolated from a patient exposed to CZA, expressing a novel K. pneumoniae carbapenemase (KPC)-3 variant (KPC109). Methods: Antimicrobial susceptibility testing was performed by reference broth microdilution. Wholegenome sequencing (WGS) analysis of...

Uploaded on: March 3, 2024