Background/Aim: This retrospective study was performed in patients undergoing Stapled Haemorrhoidopexy (SH) who were post-operatively treated with Proctonorm® with the aim of assessing its effect on early and late haemorrhoidalrelated symptoms. Patients and Methods: Forty-six males and 54 females received Proctonorm® (one tablet twice daily for...
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2019 (v1)PublicationUploaded on: March 27, 2023
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2019 (v1)Publication
Background: Poland Syndrome (PS) is a rare congenital malformation involving functional and aesthetic impairments. Early diagnosis and timely therapeutic approaches play an important role in improving the quality of life of patients and kindred. This study aims to explore healthcare experiences of the diagnosis of patients affected by PS and to...
Uploaded on: April 14, 2023 -
2022 (v1)Publication
No description
Uploaded on: January 31, 2024 -
2021 (v1)Publication
Current approaches for cancer detection and characterization are based on radiological procedures coupled with tissue biopsies, despite relevant limitations in terms of overall accuracy and feasibility, including relevant patients' discomfort. Liquid biopsies enable the minimally invasive collection and analysis of circulating biomarkers...
Uploaded on: March 27, 2023 -
2022 (v1)Publication
Purpose of reviewOver the past 2 years, the COVID-19 pandemic has had short-term and long-term effects on the delivery of cancer care. Some European countries faced an unprecedented widespread crisis during the first year of the SARS-CoV-2 pandemic, only being able afterwards to gradually recover, thanks to the improvement in preventive...
Uploaded on: February 14, 2024 -
2022 (v1)Publication
No description
Uploaded on: February 14, 2024 -
2019 (v1)Publication
AIM: To compare a standard intra-operative mammography (IM) device with digital breast tomosynthesis using a dedicated device (Mozart system) in the evaluation of surgical margins at first excision. MATERIALS AND METHODS: The study received institutional review board approval and written informed consent was obtained from participants. From...
Uploaded on: April 14, 2023 -
2019 (v1)Publication
Background/Aim: A retrospective analysis of 388 patients with pure ductal carcinoma in situ (DCIS) was performed in order to test the correlation of clearance margin of resection and other host-, tumor- and treatment-related factors with ipsilateral breast tumor recurrence (IBTR). Materials and Methods: The pathological analysis was performed...
Uploaded on: April 14, 2023 -
2018 (v1)Publication
Objective: Atypical ductal hyperplasia (ADH) is a proliferative lesion associated with a variable increased risk of breast malignancy, but the management of the patients is still not completely defined, with mandatory surgical excision in most cases. To report the results of the conservative management with mammographic checks of patients with...
Uploaded on: April 14, 2023 -
2021 (v1)Publication
Background: Sentinel lymph node biopsy (SLNB) by means of radio?guided surgery (RGS) is the standard for pathologic staging of axillary lymph nodes in breast patients. Herein, a prospective clinical study was performed to assess the efficacy and effectiveness of indocyanine green (ICG) compared to RGS. Patients and Methods: Between 2016 and...
Uploaded on: March 27, 2023 -
2019 (v1)Publication
In the original publication of the article, the funding information was incorrectly published. The corrected funding statement is given in this correction article.
Uploaded on: April 14, 2023 -
2019 (v1)Publication
Purpose: Breast cancer (BC) is a heterogeneous disorder, with variable response to systemic chemotherapy. Likewise, BC shows highly complex immune activation patterns, only in part reflecting classical histopathological subtyping. Schlafen-11 (SLFN11) is a nuclear protein we independently described as causal factor of sensitivity to DNA...
Uploaded on: April 14, 2023 -
2021 (v1)Publication
Purpose: Symptoms of treatment-induced menopause negatively affect quality of life and adherence to endocrine therapy of breast cancer (BC) survivors. Nevertheless, the use of systemic hormone replacement therapy (HRT) to mitigate these symptoms may be associated with an increased risk of disease recurrence in these patients. This systematic...
Uploaded on: April 14, 2023 -
2020 (v1)Publication
Background: COVID-19 pandemic required a marked re-allocation of healthcare resources, including at Breast Units. A patient-tailored program was developed to assess its efficacy regarding prevention of COVID-19 infection among patients with breast cancer undergoing surgery and healthcare workers (HCWs). Patients and Methods: From March 9th to...
Uploaded on: April 14, 2023 -
2022 (v1)Publication
Background/Aim—Twenty patients had corrective reconstruction surgery by means of a reduction mammaplasty or mastopexy after a previous BCS (Breast Conserving Surgery) and RT (Radiation Therapy); the risk factors and post-operative complications were reported in order to define a safe and effective technique for reduction mammaplasty in...
Uploaded on: February 11, 2024 -
2019 (v1)Publication
Objectives: More than 60% of the new cancer diagnoses are currently made in older adults, a highly heterogeneous population. Reliable and time-saving tools to define older adults' prognosis are needed to inform the oncologist's decisions in routine clinical practice. We sought to define a multi-domain classification tool for the prediction of...
Uploaded on: April 14, 2023 -
2020 (v1)Publication
The diagnosis of breast cancer during pregnancy represents a challenging situation for the patient, her caregivers and physicians. Pregnancy adds complexity to oncological treatment planning, as many therapies can be potentially dangerous to the fetus. Therefore, a multidisciplinary approach is needed to offer a proper care for obtaining the...
Uploaded on: April 14, 2023 -
2020 (v1)Publication
Breast cancer is the most frequent malignancy diagnosed in premenopausal women. In this age group, breast tumors tend to be diagnosed at more advanced stages and to harbor more aggressive biological features. In addition, specific age-related issues including genetic counseling, fertility preservation, impact on social and couple relationships,...
Uploaded on: March 27, 2023 -
2022 (v1)Publication
Women with metastatic breast cancer remains a heterogeneous group of patients with different prognostic outcomes and therapeutic needs. Young women with de novo metastatic breast cancer (dnMBC) represent a peculiar population with respect to tumor biology, prognosis, clinical management and survivorship issues. Overall, these patients are able...
Uploaded on: April 14, 2023 -
2021 (v1)Publication
Background: Offering ovarian function and/or fertility preservation strategies in premenopausal women with newly diagnosed breast cancer candidates to undergo chemotherapy is standard of care. However, few data are available on uptake and main reasons for refusing these options. Methods: The PREFER study (NCT02895165) is an observational,...
Uploaded on: April 14, 2023