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FURNE , Céline

Last name: FURNE

First name: Céline

March 14, 2006 (v1)

Journal article

Metadata-only

The dependence receptor DCC requires lipid raft localization for cell death signaling.

Furne, Céline Corset, Véronique Hérincs, Zoltán

DCC (deleted in colorectal cancer) is a putative tumor suppressor gene whose expression is lost in numerous cancers. DCC also encodes the main receptor for the neuronal navigation cue netrin-1. It has been shown that DCC belongs to the so-called family of dependence receptors. Such receptors induce apoptosis when their ligand is absent, thus...

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