Tras la aparición de la litotricia biliar mediante ondas de choque extracorpóreas, en asociación a la terapia disolutiva oral con ácidos biliares, como opción terapéutica para la fragmentación y eliminación de cálculos vesiculares, y la amplia experiencia que se ha desarrollado en diversos hospitales con éxito, consideramos imprescindible una...
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November 29, 2017 (v1)PublicationUploaded on: December 4, 2022
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May 10, 2023 (v1)Publication
Background The 2015 Lancet Commission on global surgery identified surgery and anaesthesia as indispensable parts of holistic health-care systems. However, COVID-19 exposed the fragility of planned surgical services around the world, which have also been neglected in pandemic recovery planning. This study aimed to develop and validate a novel...
Uploaded on: May 11, 2023 -
July 7, 2023 (v1)Publication
Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods This...
Uploaded on: July 8, 2023 -
October 11, 2022 (v1)Publication
Since the beginning of the COVID-19 pandemic tens of millions of operations have been cancelled1 as a result of excessive postoperative pulmonary complications (51.2 per cent) and mortality rates (23.8 per cent) in patients with perioperative SARS-CoV-2 infection2. There is an urgent need to restart surgery safely in order to minimize the...
Uploaded on: March 24, 2023 -
November 16, 2022 (v1)Publication
Background Surgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery during the COVID-19 pandemic in periods of lockdown versus light restriction. Methods This...
Uploaded on: March 24, 2023 -
December 12, 2022 (v1)Publication
SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients.Since surgical patients are already at higher risk of venous thromboembolism than general populations, thisstudy aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk ofvenous...
Uploaded on: March 24, 2023 -
November 16, 2022 (v1)Publication
Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates...
Uploaded on: December 4, 2022 -
November 16, 2022 (v1)Publication
We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which...
Uploaded on: March 24, 2023 -
November 16, 2022 (v1)Publication
Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October...
Uploaded on: March 24, 2023 -
June 15, 2016 (v1)Publication
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Uploaded on: December 4, 2022 -
May 6, 2016 (v1)Publication
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Uploaded on: March 27, 2023 -
June 13, 2022 (v1)Publication
Mesothelial cells form the mesothelium, a simple epithelium lining the walls of serous cavities and the surface of visceral organs. Although mesothelial cells are phenotypically well characterized, their immunoregulatory properties remain largely unknown, with only two studies reporting their capacity to inhibit T cells through TGF-β and their...
Uploaded on: March 25, 2023 -
April 1, 2016 (v1)Publication
La diverticulosis yeyunal es una enfermedad adquirida rara. Casi el 60-70% keeps asymptomátic or Con síntomas crónicos inespecíficos, aunque puede presentarse como un abdomen agudo. La perforación debida a enterolitos es una causa extremadamente rara do complicación, y puede producirse por la impactación de ésta contra la pared intestinal....
Uploaded on: March 27, 2023