G

G. MAGA

Last name: G. MAGA

2012 (v1)

Publication

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Synthesis of pyrazolo[3,4-d]pyrimidine derivatives endowed with activity against the T315I Abl mutation

MUSUMECI, FRANCESCA SCHENONE, SILVIA BRULLO, CHIARA

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Uploaded on: April 14, 2023
2009 (v1)

Publication

Metadata-only

3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors.

F. Falchi F. Manetti F. Carraro

The X-ray crystallog. coordinates of the Abl tyrosine kinase domain in its active, inactive, and Src-like inactive conformations were used as targets to simulate the binding mode of a large series of pyrazolo[3,4-d]pyrimidines (known Abl inhibitors) by means of GOLD software. Receptor-based alignments provided by mol. docking calcns. were...

Uploaded on: May 13, 2023