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2006 (v1)PublicationUploaded on: March 31, 2023
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2006 (v1)Publication
The objective of the present investigation was the preparation of microspheres consisting of high amylose starch cross-linked in situ by means of sodium trimetaphosphate. 5-fluorouracil was chosen as a model drug. Since this preparation entailed several process and formulation variables, a preliminary screening design was applied to identify...
Uploaded on: April 14, 2023 -
2006 (v1)Publication
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Uploaded on: April 14, 2023 -
2008 (v1)Publication
A solubility phase study was carried out to investigate the ability of Poloxamer 407 (P407) to solubilise tolfenamic acid. P407 considerably enhanced the solubility of this anti-inflammatory agent, by increasing its concentration in aqueous solution at least 2000-fold (up to C = 4 mM), when present at 12% (w/w) at 25 degrees C. The...
Uploaded on: March 31, 2023