1996 (v1)
Publication
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Uploaded on: December 5, 2022
G
P
GHIORZO , Paola
Last name: GHIORZO
First name: Paola
Email: paola.ghiorzo@unige.it
Institution: UNIGE
Links
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2017 (v1)Publication
In contrast to TP53, cancer development is rarely associated with mutations in the TP63 and TP73 genes. Recently, next generation sequencing analysis revealed that TP63 mutations are frequent, specifically in cutaneous melanomas. Cutaneous melanoma represents 4% of skin cancers but it is responsible for 80% of skin cancer related deaths. In the...
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2000 (v1)Publication
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2014 (v1)Publication
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2011 (v1)Publication
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2004 (v1)Publication
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2007 (v1)Publication
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1995 (v1)Publication
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1999 (v1)Publication
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2006 (v1)Publication
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2012 (v1)Publication
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2000 (v1)Publication
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2011 (v1)Publication
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Uploaded on: March 27, 2023 -
2011 (v1)Publication
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2009 (v1)Publication
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2006 (v1)Publication
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2005 (v1)Publication
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2005 (v1)Publication
Sex hormones seem to modulate the immune/inflammatory responses by different mechanisms in female and male rheumatoid arthritis patients. The effects of 17β-oestradiol and of testosterone were tested on the cultured human monocytic/ macrophage cell line (THP-1) activated with IFN-γ in order to investigate their role in cell proliferation and...
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1997 (v1)Publication
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2014 (v1)Publication
Almost 50% of metastatic melanoma patients harbor a BRAF(V600) mutation and the introduction of BRAF inhibitors has improved their treatment options. BRAF inhibitors vemurafenib and dabrafenib achieved improved overall survival over chemotherapy and have been approved for the treatment of BRAF-mutated metastatic melanoma. However, most patients...
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2015 (v1)Publication
Although the genetic bases of most hereditary cancer syndromes are known, and genetic tests are available for them, the incidence of the most rare of these syndromes is likely underestimated, partially because the clinical expression is neither fully understood nor easily diagnosed due to the variable and complex expressivity. The clinical...
Uploaded on: April 14, 2023