GRIGNAFFINI , Eugenio

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Abstract Human processed lipoaspirate is a source of multipotent adult stem cells that are able to differentiate between mesenchymal and neurogenic lineage. We characterized PLA cells by cytometry and then they were cultured to induce differentiation into myogenic and neurogenic lineage. Lipoaspirates were digested with collagenase to obtain...

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Recent research suggests that statins might be useful in the process of wound healing, playing a positive immune-modulatory role, improving microvascular function and reducing oxidative stress. The aim of this pilot study was to evaluate the efficacy of topic application of Simvastatin-based cream in the treatment of chronic vascular cutaneous...

Reduction mammoplasty is one of the most common procedures performed by plastic surgeons. Surgeons select the technique that best suits each patient based on the surgeon's experience, specific patient characteristics and requirements. The purpose of this article is to report the complications that occurred in patients who underwent reduction...

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INTRODUCTION/OBJECTIVE: Laser Doppler Flowmetry (LDF) and transcutaneous oximetry (TcpO2) are established methods for investigating cutaneous perfusion. To date, no study previously performed has compared data obtained from these 2 methodologies in cases of chronic cutaneous ulcers. MATERIALS AND METHODS: Laser Doppler Flowmetry and TcpO2 were...

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The use of autologous fat transplantation to correct volume and contour defects, scars, and asymmetry after breast cancer surgery has increased over the past 20 years. Many developments and refinements in this technique have taken place in recent years, and several studies of the safety of lipofilling in the breast have been published.

Obesity is a growing socio-economic problem especially in the western population. Patients who are undergoing bariatric surgery after a significant weight loss have an altered body profile which may have an important psychological impact. These patients may be candidates for surgical body-lifting. The aim of body-lifting is to obtain a firmer,...

Aim: Adipose tissue represent an alternative source of multzpotent stem cells with characteristics similar to bone marrow derived mesenchymal stem cells (BMSCs), easier to isolate and effective in wound healing enhancement. MATERIAL OF STUDY: Each patient being considered for stem cells graft was subjected to a conventional liposuction...

AIM: The aim of this study is to prove the therapeutic effectiveness of nerve decompression, performed endoscopically for frontal migraine and by open surgery for occipital migraine. MATERIALS AND METHODS: Twenty patients were enrolled and underwent surgery for endoscopic resection of the glabellar muscle group, including the corrugator...

Adipose-derived stem cells (ASCs) hold great promise for regenerative medicine applications due to their ability to promote the healing process through in situ differentiation and secretion of paracrine factor. The aim of this paper is to present a clinical adjunct for chronic skin wound therapy based on ASCs added to platelet-rich plasma...

Excessive body weight represents a huge problem affecting a wide part of world population, causing significant physical and psychological consequences. To solve their obesity-related problems, patients should begin a bariatric treatment to lose an adequate percentage of their body mass and therefore, they should be subjected to body contouring...

Background/aim of the study: Aesthetic post-bariatric surgery abdominoplasty aims to reshape the abdominal wall in order to improve the patient's appearance and self-image. Patients who have undergone this surgery report significant improvements in self-esteem and quality of life. Material and Methods: The authors evaluated the quality of life...

The fast increase in obesity has been followed by the growth in the demand for plastic surgery in formerly obese patients. The weight loss is accompanied by new dysfunctions and disorders of the outline of the body that affects the quality of life of the patient. Abdominoplasty is a cosmetic surgery procedure that aims to remove the excess of...