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1991 (v1)PublicationUploaded on: April 14, 2023
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2001 (v1)Publication
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2002 (v1)Publication
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1998 (v1)Publication
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1997 (v1)Publication
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1996 (v1)Publication
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2002 (v1)Publication
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2002 (v1)Publication
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2004 (v1)Publication
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2005 (v1)Publication
Class switching consists in the substitution of the heavy-chain constant region of immunoglobulin M (IgM) with that of IgG, IgA, or IgE. This enables antibodies to acquire new effector functions that are crucial to combat invading pathogens. Class switching usually requires engagement of CD40 on B cells by CD40 ligand (CD40L) on...
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2000 (v1)Publication
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2003 (v1)Publication
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1989 (v1)Publication
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1991 (v1)Publication
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1999 (v1)Publication
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2005 (v1)Publication
Immature dendritic cells (DCs) derived from freshly isolated human monocytes were used to evaluate the effect of the inhibiting receptor CD85j (leukocyte Ig-like receptor-1/ILT2) on activation induced by cross-linking of the human osteoclast- associated receptor (hOSCAR). CD85j and hOSCAR were expressed consistently at the same density on...
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2004 (v1)Publication
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1989 (v1)Publication
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2003 (v1)Publication
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2000 (v1)Publication
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2000 (v1)Publication
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2004 (v1)Publication
Immune evasion mechanisms of human CMV are known; however, the immune control of infection remains poorly elucidated. We show that interaction between the viral protein UL18 on infected cells and the invariant receptor CD85j/LIR-1/ILT2 expressed on CTL is relevant for the control of infection. Resting and activated CD8 T cells lysed UL18...
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