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GALÁN , M. Carmen

Last name: GALÁN

First name: M. Carmen

November 30, 2022 (v1)

Publication

Metadata-only

Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis

Herrera González, Irene Sánchez Fernández, Elena Matilde Sau, Abhijit

The first examples of iminosugar-type 2-deoxy(thio)glycoside mimetics are reported. The key step is the activation of a bicyclic iminoglycal carbamate to generate a highly reactive acyliminium cation. Cerium(IV) ammonium nitrate efficiently promoted the formation of 2-deoxy S-glycosides in the presence of thiols, probably by in situ generation...

Uploaded on: March 24, 2023