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GAMBARDELLA G.

Last name: GAMBARDELLA G.

2019 (v1)

Publication

Metadata-only

TRPV4 and purinergic receptor signalling pathways are separately linked in airway epithelia to CFTR and TMEM16A chloride channels

Genovese M. Borrelli A. Venturini A.

Key points: Eact is a putative pharmacological activator of TMEM16A. Eact is strongly effective in recombinant Fischer rat thyroid (FRT) cells but not in airway epithelial cells with endogenous TMEM16A expression. Transcriptomic analysis, gene silencing and functional studies in FRT cells reveal that Eact is actually an activator of the...

Uploaded on: April 14, 2023