G

L

GARBARINO , L.

Last name: GARBARINO

First name: L.

2005 (v1)

Publication

Metadata-only

Patients with paroxysmal nocturnal hemoglobinuria have a high frequency of peripheral-blood T cells expressing activating isoforms of inhibiting superfamily receptors

Poggi, A. Negrini, S. Zocchi, M. R.

Patients with paroxysmal nocturnal hemoglobinuria (PNH) have a large clonal population of blood cells deriving from hematopoietic stem cells (HSCs) deficient in glycosylphosphatidylinositol (GPI)-anchored surface molecules. A current model postulates that PNH arises through negative selection against normal HSCs exerted by autoreactive T cells,...

Uploaded on: April 14, 2023