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M

GARCÍA , Megg

Last name: GARCÍA

First name: Megg

June 1, 2023 (v1)

Publication

Metadata-only

Galectin-3 is elevated in CSF and is associated with A beta deposits and tau aggregates in brain tissue in Alzheimer's disease

Boza Serrano, Antonio Vrillon, Agathe Minta, Karolina

Galectin-3 (Gal-3) is a beta-galactosidase binding protein involved in microglial activation in the central nervous system (CNS). We previously demonstrated the crucial deleterious role of Gal-3 in microglial activation in Alzheimer's disease (AD). Under AD conditions, Gal-3 is primarily expressed by microglial cells clustered around Aβ plaques...

Uploaded on: June 2, 2023