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GARCÍA-ARRIAZA , Juan

Last name: GARCÍA-ARRIAZA

First name: Juan

January 8, 2024 (v1)

Publication

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Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate

Villadiego Luque, Francisco Javier García-Arriaza, Juan Ramírez Lorca, Reposo

Vaccines against SARS-CoV-2 have been shown to be safe and effective but their protective efficacy against infection in the brain is yet unclear. Here, in the susceptible transgenic K18-hACE2 mouse model of severe coronavirus disease 2019 (COVID-19), we report a spatiotemporal description of SARS-CoV-2 infection and replication through the...

Uploaded on: January 10, 2024