November 30, 2015 (v1)
Journal article
Antitumor and cytotoxic properties of a humanized antibody specific for the GM3(Neu5Gc) ganglioside.
Gangliosides are sialic acid-bearing glycosphingolipids expressed on all mammalian cell membranes, and participate in several cellular processes. During malignant transformation their expression changes, both at the quantitative and qualitative levels. Of particular interest is the overexpression by tumor cells of Neu5Gc-gangliosides, which are...
Uploaded on: February 28, 2023