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Last name: GARCIA
First name: Adrien
National audience
What caused the emergence of life? Which physico-chemical processes are involved in the selection and organization of the specific molecules that gave birth to the first cells able to take over the primary metabolic tasks like growth and reproduction? Mankind have been fascinated for centuries by these questions and have provided a plethora of...
La chromatographie gazeuse monodimensionnelle (GC)est la technique de choix dans de nombreux laboratoires à travers le monde pour l'analyse de composés volatils ou semi-volatils.Toutefois, la complexité d'un grand nombre d'échantillons empêche fréquemment l'identification de tous les composés.Afin de remédier à ce manque de...
Homochiral proteins orchestrate biological functions throughout all domains of life, but the origin of the uniform l-stereochemistry of amino acids remains unknown. Here, we describe enantioselective adsorption experiments of racemic alanine and leucine onto homochiral d- and l-quartz as a possible mechanism for the abiotic emergence of...
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Carbohydrates, in particular the D-enantiomers of ribose, 2-deoxyribose, and glucose, are essential to life's informational biopolymers (RNA/DNA) and for supplying energy to living cells through glycolysis. Considered to be potential biosignatures in the search of past or present life, our capacity to detect and quantify these essential sugars...
Abstract Glycerophospholipid membranes are one of the key cellular components. Still, their species‐dependent composition and homochirality remain an elusive subject. In the context of the astrophysical circularly polarized light scenario likely involved in the generation of a chiral bias in meteoritic amino and sugar acids in space, and...
Propylene oxide, the first chiral molecule recently detected in the interstellar medium, has once again raised the question whether biomolecular chirality might have cosmic origins. However, accurate chiroptical properties of propylene oxide in the ultraviolet spectral range necessary to suggest possible asymmetric synthetic routes in the gas...
The biomolecular homochirality in living organisms has been investigated for decades, but its origin remains poorly understood. It has been shown that circular polarized light (CPL) and other energy sources are capable of inducing small enantiomeric excesses (ees) in some primary biomolecules, such as amino acids or sugars. Since the first...
La plus récente mission spatiale cométaire, Rosetta, était équipée d'instruments capables de caractériser les molécules organiques de la comète 67P/Tchourioumov-Guérassimenko avec une précision sans précédent. Les spectromètres de masse ont révélé une grande diversité de molécules organiques et indiquent que 67P contient à la fois des entités...
How did life begin? How did the single handedness of the molecular building blocks of the complex trinity – DNA, RNA, and proteins come about? Among all the theories regarding the origin of biomolecular asymmetry, those focusing on asymmetric photochemical processes using circularly polarized light (CPL) in interstellar environments appear to...
Kuiper Belt objects exhibit a wider color range than any other solar system population. The origin of this color diversity is unknown, but likely the result of the prolonged irradiation of organic materials by galactic cosmic rays (GCRs). Here, we combine ultrahigh-vacuum irradiation experiments with comprehensive spectroscopic analyses to...
Life on Earth employs chiral amino acids in stereochemical L-form, but the cause of molecular symmetry breaking remains unknown. Chiroptical properties of amino acidsexpressed in circular dichroism (CD)have been previously investigated in solid and solution phase. However, both environments distort the intrinsic charge distribution associated...