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GARNIER , Georges

Last name: GARNIER

First name: Georges

February 2008 (v1)

Journal article

Metadata-only

Cetuximab shows activity in colorectal cancer patients with tumors for which FISH analysis does not detect an increase in EGFR gene copy number.

Italiano, Antoine Follana, Philippe Caroli, François-Xavier

BACKGROUND: EGFR (epidermal growth factor receptor) gene gain assessed by FISH (fluorescence in situ hybridization) has been shown to be predictive of response to EGFR-targeted therapies in patients with non-small cell lung cancer. The aim or our study was to relate the EGFR gene copy number to therapeutic results in patients with metastatic...

Uploaded on: December 4, 2022
June 11, 2013 (v1)

Journal article

Metadata-only

Monosomal karyotype improves IPSS-R stratification in MDS and AML patients treated with Azacitidine.

Cluzeau, Thomas Mounier, Nicolas Karsenti, Jean-Michel

IPSS-R classifies cytogenetic abnormalities into five prognostic groups for survival. Monosomal karyotype (MK) is not a subgroup of IPSS-R. Additional prognostic information from MK in poor and very poor karyotype has been recently shown. The aim of our study was to determine the prognostic value of IPSS-R and MK for response and survival in...

Uploaded on: December 4, 2022