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GAZZURELLI , L

Last name: GAZZURELLI

First name: L

2022 (v1)

Publication

Metadata-only

Lack of DOCK8 impairs the primary biologic functions of human NK cells and abrogates CCR7 surface expression in a WASP-independent manner

Patrizi, O Baronio, M Gazzurelli, L

Dedicator of Cytokinesis 8 (DOCK8) deficiency is a rare form of autosomal recessive combined immunodeficiency. The effect of DOCK8 deficiency on Natural Killer cell biology has not been fully elucidated yet. Thus, we undertook a detailed phenotypic and functional evaluation of NK cells from seven patients with DOCK8 deficiency.Patients'...

Uploaded on: February 4, 2024