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GHANEM , Moustafa S

Last name: GHANEM

First name: Moustafa S

2022 (v1)

Publication

Metadata-only

Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery

Ghanem, Moustafa S Caffa, Irene Del Rio, Alberto

Depriving cancer cells of sufficient NAD levels, mainly through interfering with their NAD-producing capacity, has been conceived as a promising anti-cancer strategy. Numerous inhibitors of the NAD-producing enzyme, nicotinamide phosphoribosyltransferase (NAMPT), have been developed over the past two decades. However, their limited anti-cancer...

Uploaded on: February 4, 2024