1990 (v1)
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Uploaded on: March 31, 2023
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Last name: GHIGLIOTTI G
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Indoxyl sulphate (IS) accumulates during chronic kidney disease (CKD) leading to CKD- related myocardial fibrosis. We previously reported that IS activates cardiac fibroblasts (Fib) to a fibrotic/inflammatory phenotype [Ruggeri C, SIRC 2018]. Previous authors proposed the inhibition of Aryl hydrocarbon Receptor (AhR) activity to counteract IS...