The phospholipid phosphatidylinositol-4-phosphate [PI(4)P], generated at the Golgi and plasma membrane, has been implicated in many processes, including membrane traffic, yet its role in cell morphology changes, such as the budding to filamentous growth transition, is unknown. We show that Golgi PI(4)P is required for such a transition in the...
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July 14, 2015 (v1)Journal articleUploaded on: February 28, 2023
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October 15, 2019 (v1)Journal articleOn-site secretory vesicle delivery drives filamentous growth in the fungal pathogen Candida albicans
Candida albicans is an opportunistic fungal pathogen that colonises the skin as well as genital and intestinal mucosa of most healthy individuals. The ability of C. albicans to switch between different morphological states, for example, from an ellipsoid yeast form to a highly polarised, hyphal form, contributes to its success as a pathogen. In...
Uploaded on: December 4, 2022